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10-Q - AGENUS INC (0001098972) (Filer)

Mon, May 12, 8:59 PM (37 days ago)

**Agenus Inc. (AGEN) Q1 2025 Financial Summary** **Financial Health and Performance Metrics:** - **Revenue:** Total revenue for Q1 2025 was $24.1 million, down from $28.0 million in Q1 2024, primarily due to a decrease in non-cash royalty revenue. - **Profit Margins:** Agenus reported an operating loss of $13.3 million for Q1 2025, an improvement from a $32.9 million loss in Q1 2024. - **Cash Flow:** Net cash used in operating activities was $25.6 million for Q1 2025, compared to $38.2 million in Q1 2024. - **Earnings Changes:** Net loss attributable to Agenus Inc. common stockholders was $25.3 million for Q1 2025, an improvement from a $61.9 million loss in Q1 2024. - **Cash Position:** Cash and cash equivalents were $18.5 million as of March 31, 2025, down from $40.4 million at the end of 2024. **Quarterly Performance Discussion:** - **Revenue Decline:** The decrease in revenue was primarily due to a $4.2 million reduction in non-cash royalty revenue related to GSK's vaccines containing the STIMULON QS-21 adjuvant. - **Expense Management:** Research and development expenses decreased by 51% to $21.5 million, and general and administrative expenses decreased by 7% to $15.7 million. - **Interest Expense:** Interest expense, net, decreased to $12.8 million, mainly due to decreased non-cash interest related to the HCR Royalty Purchase Agreement. **Trends and Uncertainties:** - **Liquidity Concerns:** Agenus has an accumulated deficit of $2.2 billion and faces substantial doubt about its ability to continue as a going concern for a period of one year after the date of filing. - **Funding Needs:** The company is seeking additional funding through discussions with operating companies and financial entities to support operations through the planned registration and launch strategy for botensilimab/balstilimab. - **Legal Proceedings:** Agenus is involved in several legal proceedings, including a securities class action lawsuit and derivative actions related to the efficacy and commercial prospects of botensilimab and balstilimab. **Future Operations Impact:** - **Clinical Trials:** Agenus is progressing with multiple clinical programs for botensilimab (BOT) and balstilimab (BAL), including registration-enabling trials in Microsatellite Stable colorectal cancer. - **Partnerships:** The company has several strategic partnerships and collaborations, including with Bristol-Myers Squibb, Betta Pharmaceuticals, UroGen Pharma, Gilead Sciences, Incyte Corporation, and Merck. - **Subsidiaries:** MiNK Therapeutics, Inc. and SaponiQx, Inc. are key subsidiaries with ongoing clinical programs and strategic initiatives. **Conclusion:** Agenus Inc. faces significant financial challenges but is actively managing expenses and seeking additional funding to support its operations and clinical trials. The company's strategic partnerships and ongoing clinical programs are crucial for its future growth and success. However, the substantial doubt about its ability to continue as a going concern highlights the need for successful fundraising and operational efficiency.